Structural Bioinformatics of the Interactome
نویسندگان
چکیده
منابع مشابه
Proteomics and Bioinformatics Soon to Resolve the Human Structural Interactome
Copyright: © 2012 Nebel JC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Following the completion of the Human Genome Project, came the humbling discovery that humans possess barely more protein-coding gene...
متن کاملBioinformatics in the human interactome project
Bioinformatics in the human interactome project 'In the early days of the Human Interactome Project, a meeting was organized.. .'. Perhaps, a few years from now, newspapers will describe in those terms how straightforward it was to plan the large-scale mapping of protein interactions in human and other model organisms. Scientists attending the second Cold Spring Harbor Laboratory/Wellcome Trust...
متن کاملAnalysis and Classification of the Structural Interactome
c © 2008 by John von Neumann Institute for Computing Permission to make digital or hard copies of portions of this work for personal or classroom use is granted provided that the copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. To copy otherwise requires prior specific permission by the publisher ment...
متن کاملStructural bioinformatics
Motivation: Protein-protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low stability and difficulty to produce the proteins and assemble them in native conformation. Thus, docking algorithms have been developed to provide an in silico approach of the problem. A protein-protein docking procedure ...
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ژورنال
عنوان ژورنال: Annual Review of Biophysics
سال: 2014
ISSN: 1936-122X,1936-1238
DOI: 10.1146/annurev-biophys-051013-022726